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Breast conserving surgery and Brca-linked breast cancer

A study from Sloan Kettering Memorial Hospital, New York and presented at the 23rd Annual San Antonio Breast Cancer Symposium demonstrated a 13% relapse risk in the breast after breast conserving surgery in patients with early breast cancer and the BRCA mutation versus a 7% local relapse rate in women with early breast cancer and no known genetic mutation. The most significant predictor of relapse in the treated breast was young age at diagnosis (and most BRCA mutation related cancers occur at young age). The risk of contralateral breast cancer was 4.4 times greater in the BRCA related breast patients.